Fundamentals of Neuroimaging: Approaches to Cognitive Impairment

Licia Pacheco-Luna, M.D., Ph.D.

Johns Hopkins Medicine, Department of Radiology and Radiological Science

Live lecture date: 03/21/2022

These learning questions are brought to you by the KnowNeuropsychology / APPCN collaboration.

*This quiz has a mixture of multiple-choice and discussion questions.

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Discussion Question: How might imaging obtained prior to your assessment inform your test selection? Conversely, how might imaging reviewed after your evaluation help you make sense of your test results?

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Discussion Question: Dr. Luna indicated that MRI is typically the preferred neuroimaging approach to assess cognitive changes. Why might be some reasons that this technique is preferred over others (e.g., CT, PET, SPECT, etc.). What might be some contraindications to MRI?

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Mr. Jackson is a 57-year-old male with a 1.5-year history of behavioral changes. Imaging revealed signs of bilateral asymmetric atrophy in the frontal lobes, with greater right-sided atrophy than left. This is suggestive of:

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Ms. Garcia is an 81-year-old woman. The radiologist examines images from a coronal slice at the level of the pons. Which level of medial temporal atrophy (MTA) would be considered abnormal?

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Newer technology allows for automatic volumetry. What is a commonly used program used to compare volume or brain structures to age, sex, and skull size?

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Dr. Luna stated that MRI is the most common form of neuroimaging to evaluate individuals with cognitive decline. The goals of neuroimaging include all of the following EXCEPT:

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